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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRAF5
All Species:
19.7
Human Site:
Y402
Identified Species:
54.17
UniProt:
O00463
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00463
NP_001029082.1
557
64406
Y402
K
L
L
E
G
T
C
Y
N
G
K
L
I
W
K
Chimpanzee
Pan troglodytes
XP_001169985
557
64480
Y402
K
L
L
E
G
T
C
Y
N
G
K
L
I
W
K
Rhesus Macaque
Macaca mulatta
B6CJY5
522
59446
K365
G
N
F
G
M
H
L
K
C
Q
E
E
E
K
P
Dog
Lupus familis
XP_537142
609
68722
Y453
K
L
L
E
G
A
C
Y
N
G
K
L
I
W
K
Cat
Felis silvestris
Mouse
Mus musculus
P70191
558
64126
Y402
K
Q
L
E
G
A
C
Y
S
G
K
L
I
W
K
Rat
Rattus norvegicus
B5DF45
530
60235
K373
G
N
F
G
M
H
L
K
S
Q
E
E
E
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509429
560
65164
Y404
K
L
L
E
G
T
C
Y
N
G
K
L
I
W
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DJN2
556
63191
C383
L
D
V
D
G
H
H
C
N
G
V
F
I
W
K
Zebra Danio
Brachydanio rerio
Q6IWL4
542
61788
Y373
R
E
L
E
A
Q
Q
Y
Q
G
I
Y
V
W
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
23.1
71
N.A.
79.5
29.4
N.A.
74.8
N.A.
28.5
23.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
42.5
77.1
N.A.
89
47.4
N.A.
86
N.A.
49
42.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
93.3
N.A.
80
0
N.A.
100
N.A.
40
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
93.3
N.A.
86.6
13.3
N.A.
100
N.A.
53.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
23
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
56
12
12
0
0
0
0
0
0
% C
% Asp:
0
12
0
12
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
12
0
67
0
0
0
0
0
0
23
23
23
0
0
% E
% Phe:
0
0
23
0
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
23
0
0
23
67
0
0
0
0
78
0
0
0
0
0
% G
% His:
0
0
0
0
0
34
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
12
0
67
0
0
% I
% Lys:
56
0
0
0
0
0
0
23
0
0
56
0
0
12
67
% K
% Leu:
12
45
67
0
0
0
23
0
0
0
0
56
0
0
0
% L
% Met:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
23
0
0
0
0
0
0
56
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% P
% Gln:
0
12
0
0
0
12
12
0
12
23
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% R
% Ser:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
12
0
0
0
0
0
0
0
12
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
78
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _